First drug treating infantile spasms is approved by the FDA
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First drug treating infantile spasms is approved by the FDA
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메디칼라이터팀
입력 2009.08.25 00:00
수정 2009.08.25 08:11
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The oral solution, Sabril [vigabatrin], has been approved by the FDA for children between the ages of one month and two years and is the first drug to treat infantile spasms which is a rare disorder leading to hundreds of seizures in children under a year old. During testing scientists believed that the disorder was caused by a deficit of gamma-amino-butyric acid (GABA) in the brain so developed the drug as a "suicide inhibitor of the enzyme gamma-aminobutyric acid transaminase" which breaks down GABA. The drug will carry a black box warning about the risk of a progressive loss of peripheral vision with potential decrease in visual acuity and will be available through a restricted distribution program.