Multiple courses of antenatal steroids are not recommended, because they decrease size at birth, reported in The Lancet. Women at high risk for preterm birth, were randomly assigned to receive multiple courses of antenatal corticosteroids (n=937) or placebo (n=921), every 14 days until week 33 or delivery. Compared with placebo group, the treatment group showed lower birth weight (2,216 vs 2,330 g, p=0.0026), shorter length (44.5 vs. 45.4 cm, p<0.001), and smaller head circumference (31.1 vs. 31.7 cm, p<0.001).